IMPORTANCE OF HERBAL DRUG FOR NEW DRUG DEVELOPMENT

Preanesthetic evaluation. Importance of herbal drug usage in anesthesia practice.

P are used widely in many countries as folk remedies, nutritional support and herbal drugs. People believe that these natural products are safe and harmless. Exaggerated news regarding herbal products is available nearly everyday in audiovisual and printed media. Combinations of herbal medicines with conventional prescribed medicines may be dangerous. Especially in the context of anesthesia, wh...

Importance of Drug Transporter Studies in the New Drug Discovery and Development

Drug transporters are expressed in many tissues, such as the intestine, liver, kidney, and the brain, and play key roles in drug absorption, distribution and excretion. In this presentation, I will summarize the significant role played by drug transporters in drug disposition, focusing particularly on their potential use during the drug discovery and development process. The use of transporter ...

the importance of clinical trials in drug development

while preclinical research answers basic questions about a drug’s safety, it is not a substitute for studies of ways the drug will interact with the human body. “clinical research” refers to studies, or trials, that are done in people 1,2. as the developers design the clinical study, they will consider what they want to accomplish for each of the different clinical research phases and begin the...

Chemical signatures and new drug targets for gametocytocidal drug development

Control of parasite transmission is critical for the eradication of malaria. However, most antimalarial drugs are not active against P. falciparum gametocytes, responsible for the spread of malaria. Consequently, patients can remain infectious for weeks after the clearance of asexual parasites and clinical symptoms. Here we report the identification of 27 potent gametocytocidal compounds (IC50 ...

Need of Innovative Approach in Herbal Drug Development